The lyrics of "Smokestack Lightning" are abstract and repetitive, invoking imagery of longing, heartbreak, and unfulfilled desire. The title itself references the smoke rising from a train’s smokestack, symbolizing movement, escape, or even a lover leaving. Aerosmith’s version adds their signature gritty rock edge, blending Steven Tyler’s dynamic vocals with Joe Perry’s blues-inspired guitar work, giving the track a modern rock vibe while honoring its blues origins.